Which dosage form is a semisolid preparation used for local application that is usually white and contains a drug distributed in both aqueous and oily components?

Which dosage form is a semisolid preparation used for local application that is usually white and contains a drug distributed in both aqueous and oily components?

• A. Gels
• B. Ointments
• C. Creams
• D. Plasters

Answer: (C)

Creams are semisolid topical preparations that are emulsions containing both oil and water phases. This dual-phase system lets the drug distribute between the aqueous and oily components, which helps with spreadability on the skin and controlled release, while giving a characteristic white, creamy appearance. They are designed for local application to the skin or mucous membranes and are less greasy than ointments but more moisturizing than gels. Gels are typically clear and mainly aqueous, ointments are oil-based and greasy, and plasters are solid adhesive sheets rather than semisolid emulsions.

Creams are semisolid topical preparations that are emulsions containing both oil and water phases. This dual-phase system lets the drug distribute between the aqueous and oily components, which helps with spreadability on the skin and controlled release, while giving a characteristic white, creamy appearance. They are designed for local application to the skin or mucous membranes and are less greasy than ointments but more moisturizing than gels. Gels are typically clear and mainly aqueous, ointments are oil-based and greasy, and plasters are solid adhesive sheets rather than semisolid emulsions.