Lipid-soluble: Ability to dissolve in lipids or fat tissue.

Lipid-soluble: Ability to dissolve in lipids or fat tissue.

• A. Lipid-soluble
• B. Minimum effective dose
• C. First pass effect
• D. Elimination

Answer: (A)

Lipid-soluble describes a drug’s ability to dissolve in fats. This property means the compound can cross lipid-rich cell membranes by passive diffusion and may accumulate in fatty tissues, influencing both how it spreads through the body and how long it remains active. In pharmacology, lipophilic (lipid-soluble) drugs often have higher distribution into tissues and can reach areas with fatty tissue or the brain more readily. The other terms refer to different pharmacokinetic concepts: minimum effective dose is about the smallest amount needed for a therapeutic effect, the first-pass effect describes hepatic metabolism that reduces oral bioavailability, and elimination is how the body removes the drug.

Lipid-soluble describes a drug’s ability to dissolve in fats. This property means the compound can cross lipid-rich cell membranes by passive diffusion and may accumulate in fatty tissues, influencing both how it spreads through the body and how long it remains active. In pharmacology, lipophilic (lipid-soluble) drugs often have higher distribution into tissues and can reach areas with fatty tissue or the brain more readily. The other terms refer to different pharmacokinetic concepts: minimum effective dose is about the smallest amount needed for a therapeutic effect, the first-pass effect describes hepatic metabolism that reduces oral bioavailability, and elimination is how the body removes the drug.